This study aims to analyze the spatiotemporal characteristics of drought (duration, frequency, severity, intensity) over Madagascar during 1981–2022 by using the Standardized Precipitation Index (SPI-3, SPI-6, and SPI-12). Additionally, impacts of drought on vegetation over the studied area were assessed based on an evaluation of the relationship between SPI and the Normalized Difference Vegetation Index (NDVI) during 2000–2022.