GRACE provided a new perspective on the anomaly monitoring of water resources. In 2003–2013, TWS in China generally followed variations in annual precipitation; it decreased in northern basins and increased in the south. In the North China Plain, human activities might have interfered with TWS's response to climate; it kept decreasing until 2012. With grid-scaled TWS, small regions with significant increasing trends were also identified in Hoh Xil and the headstream region of the Yellow River.