To resist marine submersion, coastal protection must be designed by taking into account the most accurate estimate of the return levels of extreme events, such as storm surges. However, because of the paucity of data, local statistical analyses often lead to poor frequency estimations. Regional Frequency Analysis (RFA) reduces the uncertainties associated with these estimations, by extending the dataset from local (only available data at the target site) to regional (data at all the neighboring sites including the target site) and by assuming, at the scale of a region, a similar extremal behavior. RFA, based on the index flood method, assumes that, in a homogeneous region, observations at sites, normalized by a local index, follow the same probability distribution. In this work, the spatial extremogram approach is used to form a physically homogeneous region centered on the target site. The approach is applied on a database of extreme skew storm surges and used to carry out a RFA.